Hello @Ola Næss Kaldestad ,
Thanks for taking the time to share your questions regarding the .NET framework 4.8 rollout. Based on the statement released on the Azure App Serice blog, this rollout is a non-breaking upgrade:
"The .NET Framework 4.8 update is a non-breaking in-place upgrade on App Service. No updates are required for existing applications."
However, if you do want to test your application or if you plan to re-target your application in the future to explicitly require .NET Framework 4.8 you are more welcome to do so but it is not required.
It sounds like you are fine with running your applications with 4.6.1 as their target so no action at this time is required from you. Feel free to enjoy your summer vacation! The engineering team will update this announcement periodically to inform you of the deployment progress.
hope that helps. If you have further questions please let us know.
Thanks for using Azure.
-Grace