Hi there,
Did you notice any specific Event ID in the Event viewer? You can also use the Promon to identify the exact reason for the issue. Process Monitor is an advanced monitoring tool for Windows that shows real-time file system, Registry, and process/thread activity. https://learn.microsoft.com/en-us/sysinternals/downloads/procmon
In general, SMB Multichannel relies on Windows Networking to figure out routing and creating address pairs. If you see different behavior on different servers, there's probably some minor difference in the configuration. It would be interesting to see the output of Get-SmbMultichannelConnection (and also Get-SmbMultichannelConnection -IncludeNotSelected | Select *) on both systems to dig deeper.
The below thread discusses the same issue and you can try out some troubleshooting steps from this and see if that helps you to sort the Issue. https://social.technet.microsoft.com/Forums/windowsserver/en-US/de97b95b-da28-4cdc-94c8-67b1a4d680b3/smb-multichannel-strange-behaviour?forum=winserver8gen
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