@Cor Melse Thanks for posting in our Q&A.
Based on my research, we can enable Kernel extensions via a configuration profile. Please refer to the following article:
https://learn.microsoft.com/en-us/mem/intune/configuration/kernel-extensions-settings-macos
Hope it will give you some ideas.
If the answer is the right solution, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.