Hi,@Karin Biton . Welcome Microsoft Q&A.
Here are some steps you could take to troubleshoot and potentially fix the issue:
Check Event Viewer: Look in the Windows Event Viewer for any application-related error messages or crash reports. This might provide insights into what's causing the application to fail.
Check Compatibility: Make sure that your WPF application is compatible with the version of the .NET Framework you're using (4.6.1 in this case) and any other dependencies it relies on.
Debugging: If possible, attach a debugger to your application to see where it's failing or hanging. This might provide more information about the cause of the issue.
Rollback Windows Update: Since removing the specific update (kb5011048) allows your application to work, you might consider delaying that update or looking for further information from Microsoft about any known issues with that update.
Update .NET Framework: Check if there are any updates or patches for the .NET Framework version (4.6.1) you're using. Applying the latest updates might resolve compatibility issues.
Check for Third-Party Libraries: If your application relies on third-party libraries or components, ensure that they are also compatible with the Windows update and .NET Framework version.
Check Graphics Drivers: In some cases, graphics driver updates can cause compatibility issues with WPF applications. Ensure that your graphics drivers are up to date.
Check Application Logs: If your application logs its own events or errors, check those logs to see if they provide any clues about the issue.