Hi @TFTVS ,
Unfortunately, those flags are currently experimental features, and they are only accessible at edge://flags. Currently, you won't be able to configure these flags via Intune, CMD or any PS script.
However, you can request these features to become configurable there, just by sending feedback (Alt+Shift+I) in Microsoft Edge. Then you may be able to configure them in the future releases of Microsoft Edge.
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Best Regards,
Shijie Li