Hello,
Windows Update or another updating mechanism may be automatically updating device drivers, and the new driver version might be modifying the Plug and Play capabilities. You can check the Windows Update history or any other driver update logs to see if any changes occurred around the time of the registry value modification.
Some third-party software might be managing the network adapter settings, you can check if any third-party applications related to system optimization, network management, or driver management are installed on the system.