@Vanshika Parmar, Thanks for posting in Q&A. From your description, I know we have removed the USB block policy. But the USB is still blocked. In General, Intune settings are based on the Windows configuration service provider (CSPs). The behavior depends on the CSP. Some CSPs remove the setting, and some CSPs keep the setting, also called tattooing. For USB the setting will be kept when we remove the profile.
I notice you have created the profile again with the allow setting. But it is still blocked. Please go to the following location to see if any registry key existing which can block the USB. If yes, remove them to see if the USB can be accessed.
HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\RemovableStorageDevices
Hope the above information can help.
If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.