Here are some information for your questions:
- You can check this article for for details about what ports are needed for hybrid deployment: Hybrid deployment protocols, ports, and endpoints.
- MRS proxy should be enabled on all Exchange servers.
- Do you mean select an Exchange server for the hybrid connection at the beginning of HCW? If so, you should select the newly installed Exchange server.
4) No, HCW won't delete your existing send and receive connectors. Additionally, if you choose the full hybrid configuration, new connectors will be created and the "Default Frontend" receive connector will be modified for hybrid mail flow.
5) Autodiscover record for existing SMTP domains still can be pointed your existing Exchange server.
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