Dear E.J. Oskam,
Welcome to Microsoft Community.
We understand that your Excel file notifies you to load the .xlam Excel plug-in.
According to your description, you mainly have problems when using Excel and you have tried to add the folder path to the trusted location but it did not alleviate your problem.
Usually, .xlam format files contain customized macros or VBA formula information to help you improve your work efficiency, but this operation has corresponding requirements for account and program detection during operation.
Information about macro files needs to be explained to you:
Problems related to macros and VBA require more professional technical information to help you solve them. I suggest you try to seek help in Microsoft learn (English only), where there are more experts in related fields who can provide you with better solutions.
It is designed to support advanced users like you. Many users prefer to ask questions and get more professional responses through this section.
Here is a link to a forum where you can raise specific situations and share your ideas for solving problems.
Excel Management - Microsoft Q&A
At the same time, in order to troubleshoot the operation of your Office program, you can also try the following operations:
Registry reset office
(Before resetting, please make sure all your Office files have been backed up and saved. If you use OneNote and Outlook, you need to make sure that your notes and emails are backed up to avoid file loss. At the same time, resetting will put your Office program in its initial form. The personalized settings you set need to be saved first)
After resetting, you need to log in to Office again with your Microsoft account.
Press Windows + R, enter: regedit in the run box that opens, and press Enter.
Locate the following key value and rename the Office folder (right-click it and select Rename, such as renaming Office to Officeold)
HKEY_CURRENT_USER\Software\Microsoft\Office
Then reopen the file to try the effect.
Disclaimer: Generally, modifying registry subkeys or work group is intended for advanced users, administrators, and IT Professionals. It can help fix some problems, however, serious problems might occur if you modify the registry incorrectly. Therefore, make sure that you follow these steps carefully. For further protection, back up the registry before you modify it. Then, you can restore the registry if a problem occurs. For more information about how to back up and restore the registry, clickHEREto view the article.
Best regards
Zenobia.Z | Microsoft Community Support Specialist