Hi,
If you are using a third-party antivirus solution and you're running into issues with that solution and Microsoft Defender Antivirus, you can consider uninstalling Microsoft Defender Antivirus. Before you do that, review the following resources:
See the question "Should I run Microsoft security software at the same time as other security products?" on the Windows Defender Security Intelligence Antivirus and antimalware software FAQ.
See Better together: Microsoft Defender Antivirus and Microsoft Defender Advanced Threat Protection. This article describes 10 advantages to using Microsoft Defender Antivirus together with Microsoft Defender Advanced Threat Protection.
If you determine you do want to uninstall Microsoft Defender Antivirus, follow the steps in this official article from Microsoft Microsoft Defender Antivirus on Windows Server 2016 and 2019.
Best Regards,
Sunny
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