Those are the Exchange Transaction logs and they should only be cleared by an Exchange Aware backup or by using Circular Logging.
Do not run any other type of backup against that drive.
- What are you using for backups? If so, run a full Exchange Aware backup and the logs will clear
- If you arent using a backup any longer ( since 10.21?) Then enable Circular Logging: https://learn.microsoft.com/en-us/exchange/configure-circular-logging-for-a-mailbox-database-exchange-2013-help Set-MailboxDatabase DB1 -CircularLoggingEnabled $True
WARNING: Do not enable circular logging if you are doing backups. Run a full Exchange aware backup. If you can not do that, then enable circular logging to clear the logs. Note that circular logging means you can not restore the database to the point of failure using a backup program