Hi,
Thank you for posting in Microsoft Q&A forum.
1,Is there anything changed in the environment? Please help check the SMSAdminUI.log and Smsprov.log to see if there is any further information.
2,We can add SCCM site server computer account in the SQL logins to have a try.
Open SSMS and connect to the site database, then navigate to <Server>/Security/Logins, check if the computer account is there.
If not, add it. If yes, remove it and add it back with the same setting. Then check the results.
Similar threads for your reference:
SCCM console launch fails , SQL connectivity issue with SCCM machine account
SCCM Console Cannot Connect to Database
3.Have we checked if the "C:\Program Files\Microsoft Configuration Manager\Logs" missing the administrators group and the system account?
Here is the similar thread:
ConfigMgr unable to connect to site database
Hope above information helps.
Best regards,
Simon
If the response is helpful, please click "Accept Answer" and upvote it.
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.