Copilot is available in the Home tab of Word, Excel, PowerPoint, and Outlook on the web if you are a Copilot subscriber. If you also have a Microsoft 365 subscription that includes the Microsoft 365 desktop apps then you should find Copilot available in those apps as well.
Make sure you're signed into your Microsoft 365 apps with an account that has a Copilot license.
Check if the app you want to use as the Copilot key is compatible with the operating system and device you are using.
Make sure Windows and Office Update is up to date.