Hello ScottEvans_2022,
Thank you for posting in Microsoft Community forum.
How did you check "Clients in domain B are attempting to resolve DNS, GPO, all AD requests to domain A, rather than domain B. "?
1.You can check the DNS servers on Clients in domain B? If you set the DNS servers on clients in domain B using DNS server (DC server in domain B) in domain B.
2.Check if clients in domain B can contact DCs in domain B.
3.Check if all AD ports between clients in domain B and DCs in domain B are open.
Active Directory and Active Directory Domain Services Port Requirements
Active Directory Replication over Firewalls
I hope the information above is helpful.
If you have any question or concern, please feel free to let us know.
Best Regards,
Daisy Zhou