Cost Estimate for High-Performance Azure VMs

Question

Cost Estimate for High-Performance Azure VMs

InfraSolutions 711

Assistance is needed in estimating the costs for migrating high-performance computing workloads to Azure with the following VM specifications:

CPU: 64 logical cores
RAM: 128 GB
Disk Space: 500 GB to 1 TB
Uptime: 24/7 for several weeks (on demand)

The setup will require three machines running models at 100% CPU and RAM utilization for extended periods. Performance is a priority, but cost constraints must also be considered.

Which Azure VM series will fit these requirements (Microsoft recommendations), and what would be the approximate overall cost?

Vahid Ghafarpour 23,290 Reputation points Moderator

2025-04-23T16:12:06.9166667+00:00

I think the cheapest series would be F series, like F64s, that cost you less than HB120rs.

And for sure you can use Reserved Instances for long term, or Spot VMs to save money.
InfraSolutions 711 Reputation points

2025-04-24T12:22:31.99+00:00

Thanks for your response @Vamsi Ram Annepu , @Vahid Ghafarpour

I see that the HB and HC series instances have more cores and RAM than required, which may make them an expensive choice,

For the F series, the F64s matches the requirements,

As this device is used intensely and requires high performance, will this fit? I searched in Copilot & ChatGPT (just to see what AI explains), and it is showing M series or D series. Since the same requirements display so many series, how do I pick the right choice with cost benefit? Any suggestions, please?
InfraSolutions 711 Reputation points

2025-04-24T13:05:36.6+00:00

I selected all categories in the Azure calculator and specified 64 vCPUs and 128 GB RAM. After filtering for Intel processors, only 2 to 3 instances matched. Does this mean the F series is the best choice compared to the D series?

Please correct me if i am wrong.
Vamsi Ram Annepu 740 Reputation points Microsoft External Staff Moderator

2025-04-26T01:15:35.9066667+00:00

Hi InfraSolutions,
Just checking in to see if there is any update on your choice depending on the previous information.

Feel free to reach out if you have any further queries.
Vamsi Ram Annepu 740 Reputation points Microsoft External Staff Moderator

2025-04-28T16:55:42.2366667+00:00

Hi InfraSolutions,
Just checking in to see if there is any update on your requirement

Feel free to reach out if you have any further queries.
InfraSolutions 711 Reputation points

2025-04-28T17:12:41.0966667+00:00

It looks like this page has clarified my queries, but I don't see an option to 'Accept Answer'

Accepted answer

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Vahid Ghafarpour 23,290 Reputation points Moderator

2025-04-23T16:12:06.9166667+00:00

I think the cheapest series would be F series, like F64s, that cost you less than HB120rs.

And for sure you can use Reserved Instances for long term, or Spot VMs to save money.
InfraSolutions 711 Reputation points

2025-04-24T12:22:31.99+00:00

Thanks for your response @Vamsi Ram Annepu , @Vahid Ghafarpour

I see that the HB and HC series instances have more cores and RAM than required, which may make them an expensive choice,

For the F series, the F64s matches the requirements,

As this device is used intensely and requires high performance, will this fit? I searched in Copilot & ChatGPT (just to see what AI explains), and it is showing M series or D series. Since the same requirements display so many series, how do I pick the right choice with cost benefit? Any suggestions, please?
InfraSolutions 711 Reputation points

2025-04-24T13:05:36.6+00:00

I selected all categories in the Azure calculator and specified 64 vCPUs and 128 GB RAM. After filtering for Intel processors, only 2 to 3 instances matched. Does this mean the F series is the best choice compared to the D series?

Please correct me if i am wrong.
Vamsi Ram Annepu 740 Reputation points Microsoft External Staff Moderator

2025-04-26T01:15:35.9066667+00:00

Hi InfraSolutions,
Just checking in to see if there is any update on your choice depending on the previous information.

Feel free to reach out if you have any further queries.
Vamsi Ram Annepu 740 Reputation points Microsoft External Staff Moderator

2025-04-28T16:55:42.2366667+00:00

Hi InfraSolutions,
Just checking in to see if there is any update on your requirement

Feel free to reach out if you have any further queries.
InfraSolutions 711 Reputation points

2025-04-28T17:12:41.0966667+00:00

It looks like this page has clarified my queries, but I don't see an option to 'Accept Answer'

Answer 1

Vamsi Ram Annepu 740 Microsoft External Staff Moderator

Hi InfraSolutions,
HB-series (CPU: up to 64 logical cores) or HC-series (CPU: up to 44 logical cores) or F-series (CPU: up to 72 logical cores) virtual machines are recommended for high-performance computing workloads with the specifications you provided.
Each of these have RAM according to your requirement.
You can check the disk space with the cost by visiting this link https://azure.microsoft.com/en-in/pricing/details/managed-disks/
The price is determined on various factors such as region, Pricing model which you can go through the below link https://azure.microsoft.com/en-in/pricing/details/virtual-machines/windows/#pricing
you can also check for other VM specifications using the above links

Feel free to reach out if you have any further queries.

If you found the information useful, please click "Upvote" on the post to let us know.

Vamsi Ram Annepu 740 Reputation points Microsoft External Staff Moderator

2025-04-24T18:24:38.7666667+00:00

Hi InfraSolutions,
As you feel that HB and HC series instances have more cores and RAM than required, which may make them an expensive choice, then the F-series is one of the most cost-effective choice for your specifications.

Feel free to reach out if you have any further queries.

If you found the information useful, please click "Upvote" on the post to let us know.
Vamsi Ram Annepu 740 Reputation points Microsoft External Staff Moderator

2025-04-28T23:16:18.12+00:00

Hi InfraSolutions,
Thank you for confirming that the information was useful.
Could you "Upvote" and "Accept answer" here to help the community.

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Cost Estimate for High-Performance Azure VMs

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