Hi,
A Windows Installer patch (.msp file) is a file used to deliver updates to Windows Installer applications. The patch is a self-contained package that contains all the information required to update the application.
A patch package contains the actual updates to the application and describes which versions of the application can receive the patch.
Method 1:
Refer to the article and try to run the troubleshooter:
Fix problems with programs that can't be installed or uninstalled
http://support.microsoft.com/mats/Program_Install_and_Uninstall
Method 2:
Refer to the article and check if it helps:
Update, patch | Acrobat, Reader 10.x | Windows, Mac OS
http://helpx.adobe.com/acrobat/kb/update-patch-acrobat-reader-10.html