Hi RobertJubb-3334,
As TomPhilips mentioned, each new CU contains all the fixes that were included together with the previous CU for the installed version of SQL Server. So you do not need to and you cannot install previous CU (KB4458621 and KB4293802) on new CU for SQL Server (KB4577775).
And this is the reason that the instance you want to patch does not let you select it.
Best Regards,
Amelia
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