I too am having this issue.
3/17/2021 2:57:24 PM : KeyValueRefresh failed: Environment: PROD, KV Url: , System.InvalidOperationException: GeoHelper.GetKeyValueEndpointFromGeoService: An exception has occurred attempting to contact Geo Service at: https://array601.prod.do.dsp.mp.microsoft.com/geo/ ---> System.Net.WebException: The underlying connection was closed: An unexpected error occurred on a send. ---> System.IO.IOException: Unable to read data from the transport connection: An existing connection was forcibly closed by the remote host. ---> System.Net.Sockets.SocketException: An existing connection was forcibly closed by the remote host