Exchange uses RPC to do may things, and the connections are ephemeral so while the initial connection from the Exchange server would always begin on the same port (135), the actual data exchange would always take place on a dynamically assigned "high port".
I haven't worked on Exchange since 2014 (I was an Exchange Server MVP for 16 years before retiring), but looking at what you posted it seems to have to do with the configuration of the application pool used by what used to be the Client Access Server (I don't know what that role's called now, sorry).
Maybe one of the Exchange folks can fill in more detail. But I wouldn't interfere with that traffic for now.