Hi,
If per discription no changes have been commited to the server, and suddenly the performance is significantly getting bad.
One potential cause is the network between this server and data was changed last three weeks causing lanterncy.
I would suggest you to open ticket with Microsoft Support , who have could investigate you system and server enviroment with remote help and other tools, they could help this more acurately. Support ticket with Microsoft https://support.microsoft.com/en-us/assistedsupportproducts
Regards,
Lukas