Hello Kaz Ng**,**
Good day! Thank you for reaching out to Microsoft community.
As per your description, it seems like, one of your users is experiencing this issue intermittently when opening emails in the "New Outlook" application. You mentioned that logging out and logging back into the user's Microsoft 365 account provides a temporary fix but does not resolve the issue permanently.
Based on the information provided, it seems like the issue might be related to authentication or cache within the Outlook application. We will need to investigate further to identify the root cause and explore potential permanent solutions.
To better understand your issue, I need some addition information so that we can narrow down the main reason and find out the root cause by working together.
Please correct me if I am wrong and I need your help on sending all the answers along with the data only via Private Messages - Microsoft Community.
- May I know your affected account type and subscription? Is it Microsoft365 business or Microsoft Personal account (outlook.com/Hotmail.com/live.com) or any third-party account?
- Could you please provide us product and version details of your Outlook?
- Which outlook platform are you using, is it New Outlook, Legacy (Classic) Outlook or OWA?
- Do you have hybrid configuration or environment? or running as fully cloud environment?
- Are you a global administrator user or an End user?
- Do you have access to Microsoft 365 Admin Center?
Note: to access private message platform, please click on this link: Private Messages - Microsoft Community.
Meanwhile, I would suggest trying the following initial steps to see the outcome:
The issue might be due to corrupted cached data. Clearing the cache might provide a more permanent solution.
The following is a method to manually clear Outlook cache in Windows 11/10:
- First, Close Outlook.
- Find the location of the cache. If you ask us, it's easy. Before continuing, please save everything you have done and then press the Windows key+R to launch the dialog box.
- Copy and paste %localappdata% \ Microsoft \ Outlook into the field, and then press Enter on the keyboard.

- Finally, navigate to the folder named Cache to view all files. Select all files in the folder, then right-click and click the "Delete" option to manually clear the cache. Skip those which are popping-up as database files while deleting.

- Open outlook to if you are getting same issue or not.
Ensure that both the Outlook client and the Office suite are up to date to rule out any bugs or compatibility issues.
Repairing the user's profile could address any corrupted data or configuration issues.
- Repair your Outlook profile: You can try to repair your Outlook profile by going to Control Panel > Mail > Show Profiles > Select your profile > Click Properties > Click Email Accounts > select your email account > Click Repair.
- Remove the email account: Go to Control pane > Mail > Show Profiles > Remove the associated profile.
- Clear the Windows Credential Manager: Go to Control Panel > User Accounts > Credential Manager. Under "Windows Credentials," remove any credentials related to your email/ user account.
- Disconnect Work or School Account: Select Start > Settings > Accounts > Access work or school > Select the account you wish to remove > Select Disconnect. Restart the Computer.
Try recreating the Outlook profile from scratch:
- Create a New Outlook Profile: If the profile is missing, try creating a new Outlook profile. You can do this by going to Control Panel > Mail > Show Profiles > Add. Follow the prompts to create a new profile.
- Try opening Outlook with your credentials. You should be able to access your Outlook account. If you're still unable to load your Outlook profile, please inform us. Additionally, let us know if you're able to log in to Outlook on the Web (How to sign in to Outlook on the web - Microsoft Support). It is important to know whether your Exchange mailbox is still working or not.
Please follow these steps and let me know the outcome. If the issue persists after completing the above, feel free to reach out, and we can further investigate the problem together.
Please understand that our initial response may not always resolve the issue immediately. However, with your help and more detailed information, we can work together to find a solution.
Thanks for choosing the MS community.
Looking forward to your response and have a great day ahead!!
Sincerely
S M Nazmun Nur | Microsoft Community Moderator