Hi,
Thank you for posting in Microsoft Community. As I understand, you are unable to open a particular Excel file which is downloaded from the Google docs.
Since the issue occurs with a particular file, it might be file specific issue.
Just a quick question:
What is the format of the File?
Save the file locally on the system and then try to open the file and check if it opens fine.
Right click on the saved file, click on Properties and uncheck the option Block and then try to open the file and check.
If you are still unable to open the file in Excel then open the file in CSV format, save the file as Excel file (.xlsx) and then try to open the file and check.
I hope the above suggestions helps to resolve your issue. If you need any further assistance reply and we will be glad to assist you.
Thank you.