Turns out the expired self-signed Exchange Server Cert may have been the issue after all... https://learn.microsoft.com/en-us/exchange/troubleshoot/administration/cannot-access-owa-or-ecp-if-oauth-expired
Note on the above referenced article: the sample publishes the new cert to ALL Org Exchange Servers; use with caution if you only want it pushed to a single server.
Thanks for reading!
SteveInReno