Yes, you can upgrade from Office 2019 to Microsoft 365 Apps without having to reinstall everything. You can use Group Policy or Intune Configuration Service Provider (CSP) settings to upgrade Office 2019 to Microsoft 365 Apps for enterprise without deploying a separate installation package. This method utilizes the existing Office installation and updates it to Microsoft 365 Apps.
To do this, you need to enable the Group Policy setting Upgrade Office 2019 to Microsoft 365 Apps for enterprise and specify the desired update channel. The upgrade process may take several days to complete as it depends on Office's update checks.
Additionally, you can also deploy an upgrade package using the Office Deployment Tool, which can be configured to remove existing versions of Office during the upgrade process.
Make sure to assess your devices' readiness for the upgrade and plan accordingly to minimize disruptions during the transition.