Ran Repair Office, both options.
Did have offline mapped drives, so they are now deleted.
Excess Formatting - not an issue, really simple files refuse to load
Check for Updates - have uninstalled & reinstalled Office365 . . . several times.
If I open in safe mode, Options > Advanced is greyed out & not available, opened in normal mode but hardware graphics acceleration is not listed.
Deleted OfficeFileCache & Wef folders, no Licensing folder found.
Current situation:
Still takes 30 - 40 seconds to load, even then much of the ribbon options are greyed out.
If I try to load the simplest of files I get "Not enough memory to complete this action" error.
It will work in Safe mode, still 30 seconds or so to load, but files WILL load so I can limp along.