Hi Mark Premo,
To help us troubleshoot this effectively, we’ll need a bit more information. In particular, the exact error message you’re seeing would be very helpful.
In the meantime, please check the following:
- Ensure your PC is fully up to date by installing the latest Windows updates. -> Install Windows Updates – Microsoft Support
- Verify whether any third‑party antivirus software is installed. Having another antivirus product on the device can cause Microsoft Defender Antivirus to switch to disabled or passive mode. -> Microsoft Defender Antivirus compatibility with other security products – Microsoft Learn
Run a scan to repair any potentially corrupted system files, which can also impact Defender functionality.
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