Try restarting your PC and repairing your Microsoft 365 install (Control Panel → Programs → Microsoft 365 → Change → Quick Repair), as this usually fixes Outlook not opening with Copilot.
Outlook Problem
Carlos Webster
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Reputation points
Out look will not open when i use 365 or the copilot
Outlook | Windows | Classic Outlook for Windows | For business
3 answers
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Hal Hostetler MVP-Outlook 11,896 Reputation points MVP Volunteer Moderator2026-02-20T17:17:48.1333333+00:00 What happens when you try? Do you get any error message(s)? Try starting in Safe Mode by holding down the CTRL key while launching Outlook; does it start? Do you have a POP account in your profile?
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Q&A Assist2026-02-20T15:55:33.6833333+00:00 AI generated content. This question contains an answer created with AI from Q&A Assist. Learn moreIf Outlook is not opening when using Microsoft 365 or Copilot, there could be several potential causes for this issue. Here are some troubleshooting steps you can take:
- Check for Updates: Ensure that you have the latest updates installed for Microsoft 365 and Outlook. Sometimes, outdated software can cause issues.
- Repair Microsoft 365: You can try repairing your Microsoft 365 installation. This can be done through the Control Panel under Programs and Features.
- Check for Conflicting Programs: Sometimes, other applications or add-ins can conflict with Outlook. Try disabling any unnecessary add-ins or programs that might be running in the background.
- Create a New Profile: If your user profile is corrupted, creating a new Outlook profile can help resolve the issue. You can do this through the Control Panel under Mail settings.
- Reinstall Outlook: If all else fails, uninstalling and then reinstalling Outlook may resolve the problem.
If the problem persists, it may be beneficial to consult Microsoft's support resources or community forums for further assistance.
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