Hi sir. @ 루아kr,
Thank you for reaching out Microsoft Q&A community!
Some desktop applications are designed to detect the DPI of the display they are running on, especially if they are per-monitor DPI aware. Even if both monitors are set to 100% scaling and 1080p resolution, applications may still detect the physical DPI or system-recommended DPI and adjust their scaling accordingly. Windows uses information from the monitor's EDID to determine the physical DPI and may recommend a higher DPI for 4K monitors, even if you manually set it to 100%. Per-monitor DPI aware applications will check the DPI when created and adjust their scale factor whenever the DPI changes, so they may behave differently on each monitor.
If you want applications to ignore DPI settings, you can try changing their compatibility properties by right-clicking the application, choosing Properties > Compatibility, and enabling "Disable display scaling on high DPI settings". However, not all applications will behave identically, as their DPI awareness modes and how they handle DPI changes can vary.
Allow me to share some related official documents:
High DPI Desktop Application Development on Windows - Win32 apps | Microsoft Learn
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T&R,
Kate.