Hi Johannes,
Thanks for posting your question here. I understand your situation especially that Lotus SmartCenter helps you with your everyday work.
I would like to kindly inform you that Windows 11 may classify it as “untrusted” and prevent it from starting because of Smart App control feature. Lotus SmartCenter has not been updated for many years, which can look like the app was deactivated. Please check whether this is the cause:
You can check whether Windows security is blocking the app by opening Settings, then navigating to Privacy & security, select Windows Security, then App & browser control, and opening Smart App Control settings. If Smart App Control is turned On, switching it Off may allow the app to run again however, please note that this reduces system protection and, in some cases, cannot be re‑enabled without reinstalling Windows.You may check this link for reference: App & browser control in the Windows Security App
Let me know if you have more questions, I'm here to help.
Thanks,
Jobelle C.