Hello @Robert
KB5101684 is an optional non-security preview cumulative update for Windows 11 24H2/25H2, released July 28, 2026. Microsoft also states that it can be manually imported into WSUS; it isn't included automatically as a WSUS image/update synchronization item.
Microsoft KB5101684 release notes: https://support.microsoft.com/en-us/servicing/os/windows-11/2026/07/july-28-2026-kb5101684-preview?
So if KB5101684 was deployed through your WSUS environment, I would first check how it was imported and approved, particularly whether Preview updates are being approved for production endpoints.
Regarding Cisco ISE, Microsoft can't guarantee that every third-party product will immediately support changes introduced by a Windows preview update. Cisco ultimately determines ISE/Posture compatibility with specific Windows builds and components.
Since uninstalling KB5101684 restored ISE posture functionality, that's useful evidence of a compatibility issue. I would recommend:
- Decline/unapprove KB5101684 in WSUS for affected systems for now.
- Open a Cisco TAC case and confirm whether your ISE/Posture version supports Windows builds 26100.8973 / 26200.8973.
- Test preview updates against ISE/Posture in a pilot group before broader WSUS approval.
- Wait for Cisco compatibility guidance or the subsequent Windows cumulative update before production deployment.
Microsoft currently lists no known issues for KB5101684, so the Cisco ISE behavior isn't presently documented as a known Windows issue.
Given your successful rollback test, I'd treat this as a Windows/Cisco ISE interoperability issue until either Microsoft or Cisco confirms otherwise.
Please "Accept the Answer" if this information helped you. This will help us and others in the community as well.