A family of Microsoft spreadsheet software with tools for analyzing, charting, and communicating data
Based on the information you provided, I understand that Excel does not open in normal mode but opens successfully in Safe Mode. You have already uninstalled and reinstalled Office and disabled all Excel and COM add-ins, but the issue persists.
Could you please provide the following information?
- Which version and build of Excel are you currently using?
- Which version and build of Windows are you using?
- When you start Excel normally, do you receive a specific error message, or does the application simply remain running in the background without displaying a window?
- Does the issue affect all Excel files, including a new blank workbook, or only certain files?
Because Excel still opens in Safe Mode, the issue may be related to a corrupted Excel user configuration, an XLSTART file, a customized toolbar file, or another application running in the background.
Please try the troubleshooting steps in the following Microsoft Support article:
Excel not responding, hangs, freezes, or stops working
If the problem continues, please create a new Windows user profile, sign in to it, and test Excel again. If Excel opens normally in the new profile, the issue is most likely related to a corrupted setting or file in the original Windows user profile.
Please let me know the results so we can narrow down the cause.