Greetings, Nigel! My name is Arif, and I will assist you today.
Based on your explanation, it appears that you've already attempted some steps to resolve the issue. Have you tried using an external keyboard on the same computer, and does it work properly? In most cases, when certain keys on a keyboard are not functioning, it's more likely to be a hardware issue rather than a software problem.
To troubleshoot the hardware, follow these steps:
Press the Windows key + I to open Settings.
Click on "System."
Choose "Troubleshoot."
Under "Other troubleshooters," select "Keyboard," and click "Run."
If the external keyboard functions correctly and the hardware troubleshooting indicates a hardware problem, I regret to inform you that you will need to take your brother's computer to a hardware repair shop or contact the manufacturer's service center to have them inspect and potentially replace the keyboard.
Warm Regards,
Arif