Microsoft Graph
A Microsoft programmability model that exposes REST APIs and client libraries to access data on Microsoft 365 services.
10,580 questions
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Does Microsoft offer any API to create Office 365 accounts, set subdomains, set signatures, delete accounts...? I saw Microsoft Graph API but It doesn't offer these features.
Microsoft Graph API is the API that gives you access to Microsoft 365 (Formerly Office 365). From your description:
You can state what Microsoft 365 (Formerly Office 365) plan you are one to get a better answer.
The other actions like set signatures will depend on the M365 service you want to set that on. Graph is a gateway so features have to be supported by the target M365 service.