Hi,
I can reproduce this error in my environment. Have you tested using other accounts, such as the windows administrator account, or create a new windows user locally.
In addition, have you installed and configured IIS on your computer? If IIS is not installed or configured correctly, you should see a warning on the home page of the Master Data Services Configuration Manager.
You can refer to the following links:
Enable IIS on Windows 10- Internet Information Services
You can turn on the services which displayed in the Master Data Services Configuration Manager warning, in Control panel> Programs> Programs and Features> Turn Windows features on or off> Internet Information Services> World Wide Web Services .
Master Data Services on Windows 10
SVC Handler mapping error in MDS Configuration Manager
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