Hi,
- You can right click on the Program > then select Run as Administrator.
- Ask the Program Manufacturer if it is Vista Compatible.
We can't assist you with that as Microsoft no longer has the Vista Compatibility Center link available.
- If the Program is not Vista Compatible, install it in the XP, etc Compatibility Mode
"Using Windows 7 or Vista Compatibility Mode"
http://www.howtogeek.com/howto/windows-vista/using-windows-vista-compatibility-mode/
Cheers.