Hi and thanks for reaching out. My name is William. I'm a Windows technical expert. I'll be happy to help you out today.
The error message indicates that the setup cannot continue because there is another process running. InstallShield setup.exe is just a wrapper for MSI installers. As such, there is currently a running instance of the the local MSIexec server and until that process is closed, the InstallShield setup cannot complete.
Usually, this can be corrected with a restart. If not, then you have msiexec running at logon and you need to end any instances of that before you can run the installshield setup. To do that, launch the Task Manager > go to Details > locate any instances of msiexec.exe > select End task > run the InstallShield setup.