Dear BonnieLee3
Thanks for raising your concerns in Microsoft Community.
Based on your description, I understand that you are having trouble saving files in Office. I understand how you feel and this problem is indeed frustrating.
Usually this error message is related to the [Server Draft Location] set in Office. We can first try to manually repair this option: Open any Office component, go to [Options] > [Save] tab, select [Offline editing options for document management server files], set [Server draft location], you can try to add a local path.

If the setting cannot be modified, or the problem persists after changing the path, we can try to modify the path in the registry:
- Click [Start] > Select [Run] > Enter [regedit].
- Navigate to the following path: HKEY_CURRENT_USER\Software\Microsoft\Office\Common\Offline\Options
- Select [Options], create a new [String Value] on the right, rename it to [Location], double-click to open, and set a folder path as its value, or do not set any value for the time being.
- Then check whether the Office application can be restored to normal.
Disclaimer: Generally, modifying registry subkeys or work group is intended for advanced users, administrators, and IT Professionals. It can help fix some problems, however, serious problems might occur if you modify the registry incorrectly. Therefore, make sure that you follow these steps carefully. For further protection, back up the registry before you modify it.
Since this path is usually related to the server, I need to confirm with you what the specific version of Office is. Can you take a screenshot of the [Account] interface and share it with us through your reply?
I hope the above information is helpful to you. We are looking forward to hearing from you and will continue to assist you.
Best Regards,
Tracy - MSFT | Microsoft Community Support Specialist