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Hi Sargunan Prakash,
Thank you for reaching out to Microsoft Q & A forum.
.NET Framework 4.8.1 introduces several important enhancements over version 4.8. These include improved security through support for newer cryptographic algorithms, better accessibility features aligned with modern standards, and performance optimizations in UI rendering for WPF and Windows Forms applications. Additionally, it includes support for ARM64 devices and improved high DPI display handling. Overall, upgrading to .NET Framework 4.8.1 offers meaningful benefits in terms of security, compatibility, and user experience, while maintaining full backward compatibility with applications built on 4.8.
For more information about what's new in .NET Framework 4.8.1, refer to the official documentation: https://learn.microsoft.com/en-us/dotnet/framework/whats-new/#v481
If you have found the answer provided to be helpful, please click on the "Accept answer/Upvote" button so that it is useful for other members in the Microsoft Q&A community.