@Thomas Kastl , It looks like you’re using Web App for Containers, it uses your own Docker container, so the stack is integrated. To better assist you on this, are you deploying any specific azure-datalake template?
The App Service deployment engine automatically activates a virtual environment and runs pip install -r requirements.txt for you when you deploy a Git repository, or a zip package. How exactly are you provisioning the WebApp?
On App Servvice, Oryx running in the Build Agent installs the dependencies listed in requirements.txt into a virtual environment named antenv
. This build is carried out in a local build directory. This virtual environment produced by the above build is compressed and extracted by the runtime at the root of the container to enable the users to have an optimal build and startup time.
Kindly check this Python Build Changes for details.