According to your description, it seems that your app is unabled to run with Volume Licensed Office 2019.
The tag "office-itpro" focuses on technical questions about Office desktop applications. Besides, Office applications installed on server, such as Word and Excel could run normally.
So I suggest you check the compatibility between your app and Volume Licensed Office 2019.
Thanks for your understanding.
From the perspective of Office, it's recommended to ensure Office is updated to the latest version.
Go to Trusted Settings Center > Add-ins, do not select any one of 3 options on the right. Then go to ActiveX Settings, temporarily select the last option "Enable all controls ···".
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