Your question (and VPHAN's answer) is about an access denied error opening a folder.
But the image that you posted shows a corrupt .xlsx file error. Two different problems.
MS support (and forum users) can't fix that other than to tell you that your best option is to restore the file from any backup that you have.
There are sites on the net that document methods to repair corrupted Excel files which you can try.
https://www.bing.com/search?q=fix+corrupted+excel+file
I would suggest that you first try to verify that the file contents at least looks like a .xlsx file. Download the strings utility and save it to your favorite utility folder.
https://learn.microsoft.com/en-us/sysinternals/downloads/strings
Open a command prompt and run it.
strings -n 8 "c:\your-folder-name\name-of-the-spreadsheet.xlsx"
Verify that you see "[Content_Types].xml" and other instances of "xl/worksheets".
Check other .xlsx files that you have too.
If you don't see those characters, then something must have overwrote the file contents. In that case your data is gone.
If you see this, then the data is in xls format. Rename the file from .xlsx to .xls and try again.
You image also shows "Excel (Product Activation Failed)". I would recommend that you use a properly registered version of Excel.