Hi,
Step 1: Run the Microsoft fix it from the following article:
http://windows.microsoft.com/en-US/windows-vista/Troubleshoot-printer-problems
Step 2: Check if the cartridge is properly inserted. Refer to the user’s manual or you may need to contact the printer manufacturer.
Lexmark support link: http://support.lexmark.com/index?channel=supportAndDownloads&page=home&locale=en&userlocale=EN_US