Welcome to our forum!
Looks like your issue is more related to Outlook development, please kindly understand that the Outlook tag here we mainly focus on general issues about Outlook desktop client. And not much is known about development, the following is for reference only.
- Yes, you are free to use any 128-bit GUID/Namespace in the 0x8000 range to set a custom named property.
- The scope of the GUID/namespaces is typically limited to your specific application or tenant. In some cases, the GUID may be shared within the tenant, meaning it could be accessible to other applications or services within the same tenant. By default, the GUIDs you generate aren't shared with other tenants or applications. However, it's always a good practice to ensure uniqueness to avoid any potential conflicts.
- Unfortunately, there's currently no built-in way to check existing GUIDs directly in Office 365. For example, you can create a unique GUID through the GUID generator tool, or you can manually search for your application's properties and automate the process using scripts.
If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.