Thanks for replying back.
Private Endpoints and links are highly available resources. However, since they are regional resources, any Azure region outage can impact the availability. To achieve availability in case of regional failures, multiple PEs connected to same destination resource could be deployed in different regions. This way if one region goes down, you can still route the traffic for your recovery scenarios through PE in different region to access the destination resource.
Azure Private Link frequently asked questions (FAQ)
Please let us know if you have any further queries and we can continue the discussion.