You need to install SQL Server 2012 Native Client version 11 and update the connection string and change the Provider from SQLOLEDB.1 to SQLNCLI11 as SQLOLEDB.1 doesn't support TLS 1.2
See Support for TLS 1.2 protocol in BizTalk Server.
As per KamleshKumar answer we would need to know the version of BizTalk and what CU level is installed to give a more precise answer.