Hello @Milan Mladenovic Thank you for reaching out to us on Microsoft Q&A platform. Happy to help!
Based on the information you provided, it seems that you have set up the replication appliance and installed the mobility agent on the on-premises machine that you want to replicate. You have also set up private endpoints for the services related to the migration, including the storage account used for replication.
However, you mentioned that the storage account used for replication is located in Central US, while all other resources are located in East US. This could potentially cause issues with replication, as the latency between the replication appliance and the storage account could be higher than expected.
To optimize replication performance, it is recommended to use a storage account that is located in the same region as the other resources. This can help reduce latency and improve replication performance.
If possible, you may want to consider creating a new storage account in East US and using it for replication. You can then update the replication settings for the on-premises machine to use the new storage account.
Please let us know if you have any other questions.