@Mytoast Admin,Thanks for posting in Q&A.
From your description, I know you want to disable Copilot in Microsoft Edge via Intune.
Based on my research, we can use ExtensionInstallBlocklist setting in Settings catalog in Intune to block extensions to block Copilot.
https://learn.microsoft.com/en-us/deployedge/microsoft-edge-policies#extensioninstallblocklist
Or we can use HubsSidebarEnabled setting in Settings catalog in Intune to block the sidebar to block Copilot.
https://learn.microsoft.com/en-us/deployedge/microsoft-edge-policies#hubssidebarenabled
Hope above information can be helpful.
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