Hi @EnterpriseArchitect,
Based on your description of how to use separate email accounts for work and personal purposes, you can add different profiles and turn on synchronization to achieve this function. You can refer to this link for specific information.
Additionally, in my testing, when I installed an extension in "Edge Add-ons" and switched profiles, the extension was not reinstalled. So, you can try it firstly.
I suggest you should also check if the relevant policies are used to install extensions.
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Best regards,
Jinxin Wang