SCSM 2012 R2 on Windows Server 2016 isn't officially supported by Microsoft:
https://learn.microsoft.com/en-us/previous-versions/system-center/system-center-2012-R2/dn281925(v=sc.12)?redirectedfrom=MSDN
You can give it a try with adding a new SCSM 2012R2 Management Server on Windows Server 2016.
But even if the installation is possible and maybe running without any problem for now keep in mind: It's an unsupported environment.
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Regards
Andreas Baumgarten