If I understood well your problem is that several app services in the development subscription are experiencing 500 errors, which began following a CrowdStrike incident. The errors are related to IIS being unable to access the web.config
file due to incorrect NTFS permissions and connection pool timeouts caused by all pooled connections being in use.
You may need to verify the NTFS permissions for the web.config
file are correctly set so that IIS can access it.
Then, review and adjust the connection pool settings in the connection string to accommodate the necessary number of connections and identify any long-running queries or transactions that may be holding onto connections.
Reach out to Microsoft support, they may help you.